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Senior HR Business Partner

At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.

We are seeking a dedicated Senior HR Business Partner to enhance our team with their expertise and deep understanding of HR functions. Our ideal candidate will impact every level of our organization by fostering relationships that prompt growth, facilitate innovation, and advance our dedication to an exceptional workplace culture. You will coach our leaders and managers, navigate, and resolve employee relations issues, and implement programs that help develop our employees. You will use qualitative and quantitative data to get to the bottom of issues and challenges, identify trends, and detail a narrative that enables Nautilus to ensure our employees are engaged and growing. You will be an advocate and evangelist for creating a positive employee experience, put our employees first and ensure that Nautilytes understand how people decisions are made and how that contributes to their development.

Responsibilities

  • Partner with leadership to develop and execute HR strategies that promote growth and innovation

  • Act as a consultant and provide coaching to management on employee-related matters

  • Create and facilitate leadership training workshops aimed at developing fundamental and advanced leadership skills

  • Guide managers through difficult discussions on performance, career progression, and compensation

  • Offer advice and coaching on HR policies, processes, and programs while ensuring fairness and employee advocacy

  • Drive initiatives to enhance leadership and company culture in line with our core values

  • Consult on a range of HR matters, including staffing, compensation, training, performance management, and compliance

  • Develop, lead, and deliver ad-hoc projects in collaboration with cross-functional teams

  • Work towards creating an engaging organizational environment conducive to learning and employee development

  • Anticipate employee needs and work collaboratively to develop innovative solutions for an enhanced employee experience

Qualifications

  • At least 8 years of HR Business Partner experience with a focus on performance management, organizational design, leadership coaching, and employee relations

  • Strong problem-solving skills, creative mindset, and proven ability to offer solutions for people and organizational challenges

  • In-depth knowledge of HR policies, procedures, compliance, and best practices

  • Service-oriented approach with a commitment to creating positive change and delivering exemplary employee experiences

  • Versatility in communication styles to build trust with various organizational levels

  • Proven ability to collaborate effectively with cross-functional teams and sync with the broader HR group for a seamless employee experience

  • Exceptional prioritization and organizational skills, thorough attention to detail, and a talent for juggling multiple tasks concurrently

  • Comfort with ambiguity and a proactive attitude toward pursuing creative approaches and rolling up sleeves as needed

  • Strong written and verbal communication skills

  • Experience with HCM/HRIS Systems is preferred, especially ADP, Lattice, and Ashby

Nautilus Team Culture

  • We are curious go-getters: this is a team of life-long learners who aren’t afraid to tackle the big challenges and we embrace the journey.

  • We are detail oriented: we do great science by working smart & with diligence where we learn from our trials and mistakes.

  • We are easy to work with: we want our workplace to be one where everyone can share their perspective and be treated with respect and kindness.

Nautilus Biotechnology Glassdoor Company Review
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Nautilus Biotechnology DE&I Review
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Average salary estimate

$155000 / YEARLY (est.)
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$140000K
$170000K

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Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, the company set about solving a vexing problem: how to bring true proteomics ...

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Full-time, onsite
DATE POSTED
September 9, 2025
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