Director, Performance & Digital Marketing

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.

Please Note: This opportunity is based at Guardant Health's U.S headquarters in Palo Alto, California, and is considered Hybrid Work Model-eligible.  While applicants open to relocation may be considered, this is not a fully-remote opportunity.   

Key Responsibilities

Performance Marketing & Media Strategy

• Own and optimize paid media investments across Consumer and HCP audiences, including programmatic, search, social, endemic, TV, local and emerging channels.

• Partner with Consumer and HCP Marketing leads to translate strategic priorities into integrated, performance-driven media plans.

• Manage media agencies to ensure campaigns deliver against ROI and KPI targets, with an emphasis on speed to market, testing, and optimization.

• Incorporate data-informed advanced targeting, segmentation, and personalization strategies leveraging AI and marketing automation.

• Monitor competitive media trends and adapt Shield’s media mix to maintain a leadership position.

Digital Marketing 

• Lead website strategy, optimization, and conversions to drive both consumer and HCP actions.

• Oversee CRM and marketing automation programs to nurture leads, enable segmentation/personalization, and integrate seamlessly with sales and CX systems.

• Own paid and organic social media strategy and management, ensuring alignment with brand voice, HCP and consumer strategies, regulatory requirements, and performance goals.

• Partner closely with Customer Experience and Product to ensure one unified and seamless digital experience for prospects and customers.

Technology, AI & Analytics Partnership

• Oversee digital agencies and marketing technology stack (CRM, automation, web analytics, content management, personalization tools, etc.) and ensure integration across channels.

• Partner with the Analytics team to establish KPIs, reporting frameworks, and attribution models.

• Champion AI-driven marketing initiatives, including predictive targeting, personalized content creation and delivery, and automated optimization.

Leadership & Collaboration

• Lead, coach, and inspire a high-performing performance and digital marketing team.

• Foster a fast-paced, positive, collaborative culture that thrives on learning, growth, and delivering results.

• Build strong cross-functional relationships with Consumer Marketing, HCP Marketing, Growth & Activations, Analytics, Customer Experience, Product, Sales, Communications, Medical, and Compliance teams.

• Bachelor’s degree in Marketing, Business, Communications, or related field; advanced degree preferred.

• 12+ years in performance marketing, digital marketing, and/or media strategy, ideally within healthcare, diagnostics, medical device, pharmaceutical, biotechnology, or other regulated industries.

• Proven track record managing multi-million-dollar media budgets with measurable ROI.

• Deep expertise in paid media, digital channel management, and marketing technology.

• Strong experience managing websites, conversion optimization, SEO, and CRM/marketing automation platforms.

• Understanding of HIPAA, FDA, and FTC compliance in marketing.

• Demonstrated ability to operate with speed, urgency, and adaptability in a high-growth, fast-changing environment.

• Highly collaborative with a growth mindset and comfort with ambiguity.

Success Profile

• Increased ROI, efficiency, and reach across all paid media channels.

• A high-performing pre-test experience—for both consumer and HCP audiences—that seamlessly weaves into the entire customer journey.

• Best-in-class integration of marketing technology and AI to drive personalization and performance.

• Strong, collaborative partnerships across Shield’s commercial team.

• A high-performing, motivated team that thrives in a fast-paced, results-driven culture.

Hybrid Work Model: At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The US base salary range for this full-time position is $171,360 to $235,620. The range does not include benefits, and if applicable, bonus, commission, or equity. The range displayed reflects the minimum and maximum target for new hire salaries across all US locations for the posted role with the exception of any locations specifically referenced below (if any).

For positions based in Palo Alto, CA or Redwood City, CA, the base salary range for this full-time position is $201,600 to $277,200. The range does not include benefits, and if applicable, bonus, commission, or equity.

Within the range, individual pay is determined by work location and additional factors, including, but not limited to, job-related skills, experience, and relevant education or training. If you are selected to move forward, the recruiting team will provide details specific to the factors above.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to [email protected]

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation,