Let’s get started
By clicking ‘Next’, I agree to the Terms of Service
and Privacy Policy, and consent to receive emails from Rise
Jobs / Job page
Principal Product Manager image - Rise Careers
Job details

Principal Product Manager

We are advancing AI to power the future of medicine.

At Unlearn, our purpose is to advance artificial intelligence (AI) to eliminate trial and error in medicine. We are innovating advanced machine learning methods to leverage generative AI in forecasting patient outcomes, starting with the domain of clinical trials. We produce AI-generated digital twins of individual trial participants, enabling smaller and more efficient clinical trials to bring effective medicines to patients sooner.

Our innovative work in AI today will reinvent how AI is applied in medicine tomorrow — and we have a top secret plan for how to get there. We won’t be able to achieve this mission just by applying technologies created by others; the future must be invented.

Unlearn is a technology company, not a biotech company. We use computers, not pipettes. We make and use software, we don’t discover or make drugs. We believe that AI will define the future of medicine, and we aren’t deterred by naysayers or skeptics. 

We come from a variety of backgrounds ranging from machine learning to marketing—but regardless of where we come from, Unlearners share some common traits:

  • Unlearners are ambitious; we aren’t intimidated by big, challenging goals. 

  • Unlearners are disciplined experimenters; we break down our big goals into smaller chunks and meet as often as necessary to track our velocity and iterate quickly. 

  • Unlearners are gritty; we never give up, setbacks just make us try harder.

  • Unlearners are receptive to new ideas; in fact, we hate being stuck with the status quo

  • Unlearners are storytellers; sharing information with each other and with the world is super important, too important to be boring.  And, last but not least,

  • Unlearners are team-oriented; we put the mission first, the company second, the team third, and individuals last.

Headquartered in San Francisco, Unlearn was founded in 2017 by a team of world-class machine learning scientists.  We have raised venture capital from top tier investors such as Altimeter, Insight Partners, Radical Ventures, 8VC, DCVC, and DCVC Bio, and recently completed our $50 million Series C in January 2024.

If our purpose and culture resonate with you, we invite you to apply.

About the role

We are looking for an experienced product leader who wants to help build a new, computationally-focused and AI approach to solving important problems in healthcare. The Principal Product Manager will have a broad knowledge base and the ability to converse and collaborate with different types of teams including technology, marketing, and business development, as well as the ability to develop a deep understanding of the problems our customers and users at biopharma companies encounter while running clinical trials. The ideal candidate must also have demonstrated experience with the techniques and methods of modern product discovery and product delivery.

Requirements

  • At least 8 years experience as a product manager in a technology company working on technology-powered products as a product manager

  • Bachelor’s degree or equivalent practical experience with demonstrated knowledge of the clinical development space

  • Demonstrated ability to ship high-impact products quickly, not just small features

  • Demonstrated ability to figure out solutions to hard problems with many constraints, using sound judgment to assess risks, and to lay out your argument in a well-structured, data-informed, written narrative.

  • Demonstrated ability to learn and partner with multiple functional areas of business – engineering, design, finance, sales, and marketing.

  • Strong collaboration in team environments but able to act quickly as the decision-maker

  • Technical understanding must go from the highest abstractions down to the metal

  • You find a way to get the data you need and whip it into an insightful story with no help

  • An owner’s mindset - you don’t shy away from the hard stuff

  • Passion for our mission

Nice to Haves

  • Experience in biopharma industry or in clinical development

  • Experience building and pricing platform/tools


Responsibilities

  • You'll be responsible for framing and executing the product strategy, monitoring and communicating progress, and defining functional requirements for new product experiences and features

  • Perform quantitative and qualitative research to identify product opportunities and prioritize features

  • Partner with engineering, UXR, design, and analytics teams to define, build, and iterate on new user experiences

  • Developing hypotheses for customer and uses cases, and rapidly iterating through hypotheses to find product market fit for various use cases quickly

  • Responsible for assisting with quarterly planning and assigning objectives (problems to solve) to product teams.

Benefits & Perks

The following benefits and perks are for full time roles only.

  • Generous equity participation

  • 100% company-covered medical, dental, & vision insurance plans

  • 401k plan with matching

  • Flexible PTO plus company holidays

  • Annual company-wide break December 24 through January 1

  • Commuter benefits

  • Paid Parental Leave

  • Support for H1B, TN, and E-3 Visa change of employer transfers

Unlearn is an equal opportunity employer. 

At Unlearn, we are committed to building a diverse and inclusive workplace, because inclusion and diversity are essential to achieving our mission. If you’re excited about this role, and your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply nevertheless.

Unlearn Glassdoor Company Review
No rating Glassdoor star iconGlassdoor star iconGlassdoor star iconGlassdoor star iconGlassdoor star icon
Unlearn DE&I Review
No rating Glassdoor star iconGlassdoor star iconGlassdoor star iconGlassdoor star iconGlassdoor star icon
CEO of Unlearn
Unlearn CEO photo
Unknown name
Approve of CEO

Average salary estimate

$220000 / YEARLY (est.)
min
max
$180000K
$260000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

Similar Jobs
Photo of the Rise User
Posted 22 hours ago
Inclusive & Diverse
Empathetic
Collaboration over Competition
Growth & Learning
Transparent & Candid

Mastercard is hiring a Senior Product Manager - Technical to lead hands-on API testing and validation for its global credit authorization platform.

Posted 12 hours ago

M&T Bank seeks an experienced Stablecoin Product Manager to define strategy, drive product development, and ensure regulatory-compliant stablecoin solutions for commercial banking clients.

Photo of the Rise User
Posted 13 hours ago

Clutch is hiring a Senior Product Manager to turn integrations into a scalable, productized system of certified connectors that accelerate our fintech platform.

Photo of the Rise User
Posted 20 hours ago

Fliff Inc is looking for a Texas-based Product Manager to lead end-to-end product development and deliver data-driven, customer-focused sports gaming experiences.

Photo of the Rise User
Posted 23 hours ago

Lead the strategy and execution of cloud-based digital products for Allstate Identity Protection, driving roadmap decisions, cross-functional delivery, and measurable product improvements.

Photo of the Rise User
Posted 5 hours ago

Experienced Agile Product Analyst needed to drive requirements, backlog prioritization, and agile delivery for a securities processing platform at a leading financial technology firm.

Photo of the Rise User

Lead the product strategy and execution for Vivun’s AI Sales Agent knowledge system, shaping how it learns and drives measurable adoption and ROI for enterprise sales teams.

Photo of the Rise User

Lead product strategy and delivery for CVS Caremark’s PBM pricing and underwriting tools, serving as the business-facing SME who translates complex financial and UX requirements into high-quality software.

Photo of the Rise User
Posted 21 hours ago

Lead the consumer product vision at Gladly, driving AI-enabled features and seamless user experiences across channels to enhance engagement and satisfaction.

Photo of the Rise User

Lead the Skin Health category (Hand & Body Lotion, Suncare, Sunglasses) at CVS Health with full P&L responsibility, vendor leadership, and omnichannel growth strategies.

Photo of the Rise User

Lead enterprise integrations and platform product strategy at Rho, driving new card, AP, and expense-management capabilities across multi-stakeholder partnerships.

Photo of the Rise User
Posted 16 hours ago

Lead product strategy and hands-on execution to define activation, retention, and deep engagement for Valence’s enterprise AI coaching end users.

Photo of the Rise User

Early-career product manager needed to support roadmap, requirements, and reliability for real-time communications (texting, voice, email) on a growing telecom/SaaS platform.

MATCH
Calculating your matching score...
FUNDING
SENIORITY LEVEL REQUIREMENT
TEAM SIZE
EMPLOYMENT TYPE
Full-time, hybrid
DATE POSTED
September 13, 2025
Risa star 🔮 Hi, I'm Risa! Your AI
Career Copilot
Want to see a list of jobs tailored to
you, just ask me below!