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Principal Generative AI Scientist

Lirio is a healthcare-focused AI company that builds personalization engines combining behavioral science and generative AI to improve patient engagement and health outcomes. The Principal Generative AI Scientist will lead research and engineering efforts to design, integrate, and operationalize LLM-based conversational models within Lirio’s Objective-Driven, Agentic AI Framework, collaborating closely with AI engineers and behavioral scientists to deliver safe, effective, and trustworthy patient-facing conversational solutions.

Skills

  • Deep expertise in LLMs, transformer architectures, and attention mechanisms
  • Practical experience with fine-tuning, instruction tuning, and alignment techniques
  • Experience implementing RAG, retrieval systems, and knowledge-grounding for LLMs
  • Strong background in model safety, guardrails, and evaluation for conversational systems
  • Experience with personalization techniques (embeddings, contextualization)
  • Proficiency in PyTorch and/or TensorFlow and modern ML toolchains
  • Experience with deployment and hosting of large models (cloud, containers, inference services)
  • Familiarity with RL, multi-task learning, or JEPA-style approaches
  • Excellent software engineering practices and experience collaborating with engineering teams
  • Demonstrated research output (publications, talks) in relevant ML areas

Responsibilities

  • Drive research initiatives to advance conversational AI and generative model capabilities for patient-facing applications.
  • Design, prototype, and productionize LLM-based conversational systems within the Objective-Driven Multi-Agent Framework.
  • Collaborate with behavioral scientists to ensure models leverage behavior-focused content libraries and knowledgebases in real time.
  • Implement model alignment, fine-tuning, RAG, guardrails, and safety mechanisms for healthcare dialogues.
  • Integrate personalized embeddings and contextual signals to improve individualized conversational experiences.
  • Define and implement feedback loops between conversational outputs and the behavior-based foundation model.
  • Oversee scalable, secure platform architecture and core services for generative AI deployment.
  • Contribute to research on safety, trustworthiness, and evaluation metrics for medical chatbots.
  • Work with engineering teams to follow software engineering best practices and operationalize research advances.
  • Mentor and lead cross-functional teams, and communicate technical direction to stakeholders.

Education

  • PhD in Computer Science, Computer Engineering, Mathematics, or a related field (required)
  • Advanced coursework or research in NLP, deep learning, or AI alignment
  • Ongoing engagement with research community (publications, open-source, conferences)

Benefits

  • Competitive base salary with performance-based compensation
  • Comprehensive health, dental, and vision insurance
  • 401(k) or retirement savings plan
  • Flexible PTO and remote-first work arrangements
  • Professional development and conference support
  • Equity or long-term incentive opportunities (where applicable)
  • Paid parental leave and family-friendly benefits
To read the complete job description, please click on the ‘Apply’ button
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SALARY RANGE
$220,000/yr - $300,000/yr
EMPLOYMENT TYPE
Full-time, remote
DATE POSTED
September 22, 2025
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