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Manager, Operational Excellence, Cell Therapy in Devens, MA

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here at BMS with our Cell Therapy team.

The Manager, Operational Excellence, Cell Therapy is responsible for performing functions to apply techniques and principles that will improve the end-to-end operations and supply chain processes that will

deliver best in class safety, quality, productivity and cost across the value streams. This position is intended for someone with organizational curiosity and will think beyond the current status quo. Using lean/six sigma techniques, the person in this role will drive improvements both individually and through cross functional teams for cell therapy products for both global clinical trials and commercial supply. It is key for this position to be able to translate the implementation of improvements into tangible benefits.

The Operational Excellence Manager will require knowledge and experience with the Toyota Production System including most of the key lean tools and will be responsible to drive the execution of the Site Operational Excellence Roadmap. In addition, this role will be responsible for continuously assessing and identifying improvement opportunities that could make a difference in the business, propose them and after approval and inclusion in the Site OpEx Roadmap, will be responsible for implementation.

Shifts Available:

Monday – Friday, Standard Working Hours

Responsibilities:

  • Execute and effectively deliver the Site Operational Excellence Roadmap for the Devens Facility.
  • Deploy Policy Deployment (Hoshin Kanri), Value Stream Maps, Visual Management Systems and other key lean tools.
  • Collaborate on the Growth of the Operations Excellence maturity level in the organization.
  • Analyze and identify improvement opportunities that will add value to the facility, propose them and effectively execute them.
  • Utilize business intelligence tools (e.g tableau,) and conducting advanced analytics to improve key performance metrics to achieve future desired operational capability and growth.
  • Utilize simulations software to create models to identify resources needed to support operations and identify opportunities to improve overall resource utilization and capacity.
  • Create and maintain capacity models, simulation models, and proactively drive capacity solutions.
  • Be actively present and connected with the process, where value is created.
  • Analyzes work force utilization, facility layout, and operational data such as production costs, process flow, headcount and production schedules, to determine efficient utilization of worker and equipment.
  • Support project teams, prepare project schedules, coordinate the execution of technical projects and report out to senior management.
  • Implement methods for improving efficiency and reducing waste of raw materials and utilities.
  • Design and facilitate kaizen/workshops to understand current processes, conduct route cause analysis investigation, design future state and develop change plans.
  • Conduct Gemba style process documentation and diagnostic activities.
  • Collect, consolidate, and analyze data and information, present it in a format that brings information to life and therefore supports effective decision making.
  • Work cross-functionally.
  • Work closely with Engineering /Maintenance on the design and implementation of new technology and new systems/facilities related to production process needs.
  • Foster strong inter-team relationships to achieve common project goals.
  • Support monitoring, analyzing, and optimizing the end-to-end process and anticipate and permanently resolve issues that may arise during production.
  • Provide investigation support for production related investigations, ensuring compliance with internal standards and regulatory requirements.
  • Design and execute test plans and other risk mitigation exercise as part of investigations (e.g. Root cause analysis and CAPAs).
  • Support inspection readiness and actively support regulatory inspections and ensure safe and compliant cGMP operations.
  • Review and revise the content of technical documentation (e.g. investigations, changes, SOPs and batch records).
  • Support the tracking of team metrics and manage completion of objectives and projects.
  • Drive changes across the organization.

Knowledge and Skills:

  • Experience of successfully implementing and sustaining a Lean/Continuous Improvement Initiatives.
  • Successful and demonstrable track record delivering end-to-end (from conception to benefits realization) process improvement initiatives.
  • Experience with Hoshin Kanri or Policy Deployment systems implementation is desirable.
  • Development of Value Stream Maps, Visual Management Systems and other lean tools.
  • Solid understanding of Lean Principles and Six Sigma. Engineering, Project Management and Financial acumen are desirable.
  • Vast experience with application of Operational Excellence and Lean Manufacturing principles.
  • Experience with Change Management principles.
  • Experience with Project Management principles is highly desirable.
  • Solid understanding of cGMP’s and multi-national biopharmaceutical/cell therapy regulations.
  • Experience working with external parties and/or influencing cross-functional teams.
  • Possess strong verbal/written communication skills and ability to influence at all levels.
  • Be able to train and coach others effectively.

Basic Requirements:

  • Bachelor’s degree of Engineering/Business/ Science or related discipline.
  • Lean Six Sigma Black Belt Green Belt required/Lean Six Sigma Black Belt from an accredited institution preferred.
  • Minimum 5 years of Operational Excellence experience in the Biotech/pharmaceutical industry - Cell Therapy preferred.

BMSCART

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If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

Devens - MA - US: $106,820 - $129,440


The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. 

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

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Average salary estimate

$118130 / YEARLY (est.)
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$106820K
$129440K

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Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.

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Full-time, onsite
DATE POSTED
October 5, 2025
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