If you’re looking for full-time or part-time jobs in St. Louis, now is a great time to apply. The St. Louis job market is growing quickly, with high demand across industries like healthcare, technology, education, logistics, and business administration. Whether you’re searching for entry-level roles, mid-career positions, or remote job opportunities, employers in St. Louis are actively hiring. You’ll find job openings for registered nurses, software developers, customer service reps, warehouse associates, marketing managers, and more. With a lower cost of living than cities like Chicago or New York, St. Louis offers a smart mix of career growth and financial flexibility. From corporate offices to nonprofits, and hybrid to in-person roles, St. Louis is one of the best cities in Missouri to find a new job and grow your career.
Why St. Louis is a Smart Place to Job Hunt
St. Louis might not always make the front page of job trend reports, but that’s exactly why it's a hidden gem for professionals. Here’s what makes STL a strong contender for your next career move:
Fast-Growing Job Market
If you’re looking for full-time or part-time jobs in St. Louis, you’re entering a market on the rise. The metro area has seen a 2.6% increase in employment growth year-over-year, placing it among the top 10 fastest-growing job markets in the U.S., according to recent data from the Bureau of Labor Statistics. Major employers like BJC HealthCare, Boeing, Centene, and Washington University are consistently hiring across a range of roles—from entry-level administrative jobs to high-paying positions in tech, healthcare, and logistics.
St. Louis has become a regional hub for healthcare and bioscience, home to over 50 hospitals and medical centers and more than 1,000 life sciences companies, including those supported by the Cortex Innovation Community and BioSTL. On the tech side, the city is quietly expanding its digital economy, with rising demand for software engineers, data analysts, IT project managers, and cybersecurity specialists—especially at fast-growing startups supported by Arch Grants and local accelerators.
With thousands of job openings and a business-friendly environment, St. Louis is one of the best cities in the Midwest to find new opportunities and grow your career—without compromising your lifestyle or financial future.
Lower Cost of Living = More Life Flexibility: Unlike larger cities like Chicago or New York, St. Louis offers a significantly lower cost of living—approximately 14% below the national average—according to BestPlaces. That means your paycheck goes further here, especially when it comes to housing, transportation, and healthcare expenses.
Healthcare & Bio Innovation Powerhouse: With globally respected institutions like BJC HealthCare, SSM Health, Mercy, and Washington University School of Medicine, St. Louis is one of the top healthcare hubs in the Midwest. There’s also a growing bioscience scene led by Cortex, BioSTL, and Arch Grants-backed startups.
Aerospace, Manufacturing & Logistics Roots: Home to Boeing and a dense logistics infrastructure, STL continues to create strong-paying roles in manufacturing, operations, supply chain management, and engineering.
Tech & Startup Scene That’s Gaining Ground: The city has seen a steady rise in tech jobs thanks to ecosystem builders like TechSTL, Cortex Innovation District, LaunchCode, and Arch Grants. From cybersecurity and data science to frontend development and product management, STL is no longer just a flyover for tech—it’s growing fast and hiring.
Top Employers in St. Louis
Whether you want the structure of a large organization or the career mobility that comes with industry leaders, these companies are among the largest and most active employers in the St. Louis region:
BJC HealthCare: A leading nonprofit healthcare system operating 14 hospitals and multiple community health centers. They frequently hire for registered nurses, medical assistants, healthcare administrators, clinical researchers, and patient care coordinators.
Walmart: With a robust presence in the STL metro area, Walmart hires for retail managers, warehouse associates, logistics supervisors, and corporate positions in supply chain and operations.
Washington University in St. Louis: A prestigious private research university employing thousands across roles such as academic advisors, research coordinators, IT support staff, lab technicians, and HR professionals.
SSM Health: A Catholic, not-for-profit health system employing over 10,000 professionals. Look here for nursing jobs, respiratory therapists, radiologic techs, medical billing specialists, and health IT roles.
Mercy: Mercy operates hospitals and urgent care centers throughout the Midwest, offering careers in nursing, medical imaging, behavioral health, pharmacy, and telehealth support.
Boeing: A global leader in aerospace manufacturing and defense. Boeing regularly posts jobs for aerospace engineers, software developers, mechanics, program managers, and supply chain analysts in their St. Louis facility.
Schnucks: A regional grocery chain headquartered in St. Louis. Career paths include store managers, inventory specialists, marketing analysts, and corporate HR professionals.
Edward Jones: A major financial services firm with deep roots in STL. They're hiring financial advisors, data scientists, client support associates, marketing analysts, and project managers.
Emerson Electric: Global tech and engineering giant based in St. Louis. Career opportunities include software engineers, design engineers, supply chain planners, and business development roles.
Centene Corporation: A fast-growing healthcare enterprise focused on managed care. Look for openings in claims processing, compliance, analytics, IT infrastructure, and health plan operations.
Graybar: A Fortune 500 company specializing in electrical supply and logistics. Regular roles include account managers, logistics coordinators, pricing analysts, and warehouse supervisors.
Where to Find Jobs in St. Louis
You don't have to rely solely on LinkedIn or Indeed. Here’s a curated list of platforms—some national, some local—that will give you an edge in your job search:
St. Louis Jobs on Rise
Rise is a professional job search platform powered by AI, designed to automate applications and match you to the best-fit jobs. Their St. Louis page includes tech jobs, remote jobs, and roles in healthcare, marketing, operations, and beyond.
Jobs.Mo.Gov
The official Missouri state jobs board, with listings in government, education, skilled trades, and healthcare across the STL region.
STL.works
Focused on high-paying roles without a four-year degree. Strong coverage of logistics, trades, warehousing, and construction positions.
STLJobs.com
A local job board with a mix of administrative, customer service, skilled trades, and healthcare roles.
TechSTL
A community-driven hub for STL’s tech ecosystem. Follow their newsletter and events for insider job leads and startup opportunities.
Cortex Innovation District
The biotech and innovation district posts jobs from research labs, medtech startups, and venture-backed employers.
STL Partnership Jobs Board
Find jobs in advanced manufacturing, biosciences, logistics, and public/private partnerships.
STL Nonprofit Career Center
Looking for mission-driven work? This board posts roles in education, social work, nonprofit management, and development.
BioSTL
Ideal for those in biotech, research, or health innovation. Roles include lab managers, data analysts, research associates, and startup jobs.
Handshake
If you’re a student or recent grad (WashU, SLU, UMSL), employers use Handshake to post internships, entry-level roles, and early career opportunities.
LaunchCode
Great for aspiring tech workers without a CS degree. They offer free coding bootcamps and connect job seekers to tech apprenticeships and junior dev roles.
St. Louis Startups LinkedIn Group
Under-the-radar listings and founder-to-founder hiring. Best for startup jobs, interns, marketers, and early employees.
Free Career Services & Job Seeker Resources in St. Louis
You don’t have to do this alone. These organizations offer free or low-cost support for your job search:
SLATE Missouri Career Center
Offers resume help, mock interviews, job referrals, free training, apprenticeships, and career counseling. Walk-in or schedule a 1:1 session downtown.
St. Louis Professional Community on Rise
An active community of job seekers and working professionals across the U.S. Share tips, find support, and get access to exclusive job events, career challenges, and insider company hiring insights.
St. Louis County Workforce Development
Services include job fairs, career skills training, GED completion, and employer hiring events, especially geared toward low-income or transitioning workers.
Urban League of Metropolitan St. Louis
Provides free programs like job readiness bootcamps, soft skills workshops, IT training, and career coaching.
Employment Connection
Supports underserved communities with job placement, coaching, life skills training, and connections to employers hiring reentry or nontraditional candidates.
St. Louis Public Library Career Center
Yes, your local library has a job center. Access free computers, resume templates, workshops, job fairs, and 1:1 coaching sessions.
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