Senior Systems Engineer

Synthego is seeking a skilled and forward-thinking IT Systems Engineer to help design, implement, and optimize the technology foundation that powers groundbreaking CRISPR research. This is a pivotal opportunity to advance innovation in life sciences by ensuring our scientists and engineers have secure, reliable, and high-performance systems at their fingertips. You will architect and support critical infrastructure, streamline operations, and deliver seamless user experiences across a hybrid environment. If you 

thrive at the intersection of engineering, IT, and science—pushing technology to enable discoveries that improve human health—this role is for you.

• Design, implement, and optimize secure, scalable IT solutions across a modern SaaS-first environment.

• Lead projects that align technology with business outcomes, improving efficiency, collaboration, and security.

• Administer and enhance critical platforms including Microsoft 365, Okta, AWS, Slack, and AI-enabled tools.

• Manage and support core network and security infrastructure such as Fortigate firewalls, Meraki networking, and VPN services.

• Oversee virtualization environments, including VMware, to ensure reliable and cost-effective compute resources.

• Drive automation and process improvements to streamline IT operations and reduce manual effort.

• Serve as an escalation point for complex support issues, ensuring timely resolution and minimal disruption.

• Partner with scientists, engineers, and business stakeholders to translate research and operational needs into technical solutions.

• Maintain strong security practices, including identity and access management, endpoint controls, and incident response readiness.

• Document systems, processes, and standards to support scalability, compliance, and knowledge sharing across the team.

• BS or equivalent degree in Computer Science, Information Systems, or related field

• 5+ years of experience as a Systems Engineer, IT Administrator, or similar technical role

• Proven expertise managing SaaS platforms such as Microsoft 365, Okta, Slack, and other business-critical applications

• Hands-on experience with networking and security technologies (e.g., Fortigate, Meraki) and on-premises and cloud infrastructures (AWS, VMware)

• Strong understanding of identity and access management, security best practices, and compliance requirements

• Excellent troubleshooting skills with experience serving as an escalation point for complex issues

• Adept at project execution—able to translate business needs into technical solutions that drive measurable results

• Strong communication and collaboration skills, with the ability to partner effectively across technical and non-technical teams

• Analytical and process-oriented, with a continuous improvement mindset and a focus on automation where possible

• Self-starter who thrives in a fast-paced, evolving environment and is comfortable balancing strategic projects with hands-on problem-solving

• Medical, dental, and vision benefits
• 401k Program
• Paid parental leave
• Flexible paid time off

Our Mission

Synthego® is a pioneering force in the biotechnology industry, dedicated to advancing the frontiers of CRISPR cell and gene therapies through cutting-edge CRISPR technology and expertise. Our mission is to provide unparalleled access to CRISPR solutions at scale, empowering applications from Discovery to Clinic. Driven by a visionary approach, we strive to accelerate the therapeutic development process with best-in-class CRISPR solutions, simplified licensing & expert guidance, driving the adoption and success of CRISPR-based therapies to benefit all patients.