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Automation Engineer III

The Opportunity

At insitro, we aim to bring better drugs faster to the patients who can benefit most, through machine learning and data at scale. Our platform approach pushes us to build robust, reusable and scalable capabilities allowing for a continuous flywheel of discovery.

As an Automation Engineer, you will collaborate with scientists, software engineers, and microscopy engineers to build high-quality automated systems and protocols. Reporting to the Director of Process Engineering, you'll help advance insitro's high-throughput arrayed and pooled screening processes—an essential capability of our Cellular Machine Learning (CellML) Platform.

In this role, you'll:

  • Develop and improve complex automation workflows on workstations and large-scale integrated systems.

  • Define and perform instrument qualification processes (IQ/OQ/PQ)

  • Support workflow analysis, identify bottlenecks and highlight areas for improvement

  • Support the lab teams in troubleshooting their workflows and methods. Provide root cause analysis

  • Develop software to integrate automation software with LIMS

  • Prepare and review design documents and participate in code reviews

  • Develop device drivers to facilitate workcell integration

  • Gain exposure to a wide range of technologies and approaches, broadening your technical toolkit

  • Contribute directly to insitro's mission, while shaping both our culture and our scientific outcomes

This is an onsite role based in our South San Francisco headquarters, expected to be in the office five days per week. #LI-Onsite

Join us, and help make a difference to patients!

About You

  • Bachelor's degree or higher in Robotics, Mechanical, Electrical, Chemical, Software or Bioengineering, or Physics, Chemistry or Biology. 2+ years of relevant work experience

  • You are conscientious about your commitments to your team, maintaining best practices while prioritizing team goals

  • You enjoy working together with scientific partners to iterate through solutions and support high quality data generation

  • You are comfortable learning and supporting diverse automation equipment (e.g., liquid handlers, robotic arms, plate readers, plate washers etc)

  • You have experience automating scientific workflows (ex. Genomic Screening)

  • Proficiency in Python, C# (or similar programming language)

Compensation & Benefits at insitro

Our target starting salary for successful US-based applicants for this role is $120,000 - $130,000. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data.

This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.

 

In addition, insitro also provides our employees:

  • 401(k) plan with employer matching for contributions

  • Excellent medical, dental, and vision coverage as well as mental health and well-being support

  • Open, flexible vacation policy

  • Paid parental leave of at least 16 weeks to support parents who give birth, and 10 weeks for a new parent (inclusive of birth, adoption, fostering, etc)

  • Quarterly budget for books and online courses for self-development

  • Support to attend professional conferences that are meaningful to your career growth and role's responsibilities

  • New hire stipend for home office setup

  • Monthly cell phone & internet stipend

  • Access to free onsite baristas and cafe with daily lunch and breakfast for employees who are either onsite or hybrid

  • Access to free onsite fitness center for employees who are either onsite or hybrid

  • Access to a free commuter bus and ferry network that provides transport to and from our South San Francisco HQ from locations all around the Bay Area

 

insitro is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We aim to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.

Please be aware of recruitment scams: we never request payments, all recruitment communications are from @insitro.com, and if in doubt, contact us at [email protected].

About insitro

insitro is a drug discovery and development company using machine learning (ML) and data at scale to decode biology for transformative medicines. At the core of insitro’s approach is the convergence of in-house generated multi-modal cellular data and high-content phenotypic human cohort data. We rely on these data to develop ML-driven, predictive disease models that uncover underlying biologic state and elucidate critical drivers of disease. These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, design therapeutics and inform clinical strategy. insitro is advancing a wholly owned and partnered pipeline of insights and therapeutics in neuroscience and metabolism. Since launching in 2018, insitro has raised over $700 million from top tech, biotech and crossover investors, and from collaborations with pharmaceutical partners. For more information on insitro, please visit www.insitro.com.

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Average salary estimate

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$120000K
$130000K

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Full-time, onsite
DATE POSTED
October 16, 2025
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