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Software Engineer II

Company Description

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedInX (Twitter) and Facebook.

Job Description

Position Summary:

At Guardant Health, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management.

To support Guardant Health’s leadership in disruption of cancer treatments, the Enterprise Software team is looking for an experienced and energetic full stack software engineer to build applications, products, and APIs that reach Guardant Health’s stakeholders and customers. This role follows a hybrid work schedule from our Palo Alto, CA office.

Essential Duties and Responsibilities

  • Design, build, and maintain scalable Java microservices that support enterprise data delivery.
  • Implement and extend integrations with LabVantage LIMS and other internal tools.
  • Develop and maintain customer-facing RESTful APIs and backend services for data exchange.
  • Collaborate with product management to translate requirements into production features.
  • Apply best practices in code quality, testing, and architecture; contribute to ongoing technical improvements.
  • Build and maintain automated unit, integration, and regression tests as part of regular releases.

Qualifications

  • Bachelor’s degree in Computer Science, Software Engineering, or related field.
  • 3+ years of professional software development experience.
  • 2+ years of production experience with Java or similar languages (C#, Python).
  • 2+ years of experience developing RESTful APIs and enterprise data integration solutions.
  • Strong experience with relational databases, schema design, and structured data formats (XML/JSON).
  • Hands-on experience with cloud services (AWS, Azure, or equivalent).
  • Familiarity with messaging systems (e.g., queues, topics, pub/sub).
  • Experience working in an agile development environment.
  • Knowledge of test automation and CI/CD practices.

Preferred Qualifications

  • Experience with LabVantage LIMS or similar platforms.
  • Proficiency with Java frameworks such as Spring Boot.
  • Experience with Kubernetes or containerized deployments.
  • Familiarity with data security and compliance in regulated environments.
  • Strong debugging and performance optimization skills.

Additional Information

Hybrid Work Model: At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The US base salary range for this full-time position is $103,110 to $141,780. The range does not include benefits, and if applicable, bonus, commission, or equity. The range displayed reflects the minimum and maximum target for new hire salaries across all US locations for the posted role with the exception of any locations specifically referenced below (if any).

For positions based in Palo Alto, CA or Redwood City, CA, the base salary range for this full-time position is $121,300 to $166,800. The range does not include benefits, and if applicable, bonus, commission, or equity.

Within the range, individual pay is determined by work location and additional factors, including, but not limited to, job-related skills, experience, and relevant education or training. If you are selected to move forward, the recruiting team will provide details specific to the factors above.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to [email protected]

A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

Please visit our career page at: http://www.guardanthealth.com/jobs/

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CEO of Guardant Health
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Average salary estimate

$144050 / YEARLY (est.)
min
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$121300K
$166800K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

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Full-time, hybrid
DATE POSTED
October 30, 2025
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