Staff Program Manager #4421

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in Menlo Park, California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com.

We are seeking an experienced Staff Program Manager to lead GRAIL’s end-to-end RFP, onboarding, and customer diligence (due diligence / security / compliance) processes. This role owns the intake, coordination, and delivery of high-value customer requests. You will partner with cross-functional teams—including Commercial, Security, Privacy, Compliance, Product, Finance, and Legal—to ensure timely, high-quality responses that protect GRAIL while supporting business growth.

This role drives rigorous RFP and diligence responses, smooth onboarding, and strengthened customer trust. It enables quicker deal completion by ensuring effective handling of diligence and proposal requests.

The successful candidate will balance process rigor with adaptability, driving continuous improvement while fostering strong relationships across the organization. The role will be both internal- and customer-facing, with positive influence on business outcomes.

You are approved to work remotely from your city and state. While your primary workplace is your home, you may be required to travel occasionally to a GRAIL office or other locations to perform your work or attend team-related events.

• Serve as the primary point of contact and program owner for inbound RFPs, customer onboarding coordination, and diligence assessments.
• Facilitate the bid/no-bid evaluation process in collaboration with Commercial and Legal teams, ensuring alignment on prioritization and resourcing.
• Manage timelines, oversee dependencies, and ensure submission of complete, compliant, high-quality responses.
• Partner with internal teams—including Legal, Compliance, and Security—to review and escalate non-standard terms, risk findings, regulatory or contractual red flags, and proposed mitigations.
• Maintain and enhance an internal knowledge base/content library of approved responses, templates, certification statements, processes, and controls to streamline future responses.
• Establish and oversee a centralized intake process with standardized workflows, clear SLAs, gating criteria, and escalation paths.
• Drive automation, tooling, and data/metrics for efficiency (e.g., average cycle time, win rate, risk-closure timelines, accuracy and consistency of responses, customer satisfaction with diligence responsiveness).
• Coordinate across stakeholder teams to deliver clear, timely communication regarding status, issues, dependencies, and deliverables.
• Support the customer diligence lifecycle, including questionnaire responses and reviews, onboarding assessments, audit responses, and recertifications.
• Deliver training, documentation, and onboarding for internal teams (Commercial, Customer Success, Product, etc.) on RFP/diligence protocols and best practices.
• Report statuses, risks, KPIs, and trends to leadership, interpreting insights and driving recommendations for continuous process improvements.
• Lead continuous improvement initiatives to optimize RFP and diligence processes, identify bottlenecks, and increase organizational efficiency.
• Participate in external customer calls or clarification sessions as needed during RFP proposals or diligence review processes.

• Bachelor’s degree in a relevant field (Business, Engineering, Computer Science, or related discipline) required.
• Minimum of 8 years of program/project management experience, with exposure to RFP/proposal management, vendor risk management, or security/diligence review.
• Direct experience within a regulated environment in life science or healthcare industry.
• Certifications such as CISSP, CISA, CRISC, APMP, or PMP are strongly preferred but not required.
• Demonstrated background in security, privacy, or compliance operations (especially in healthcare, biotech, or SaaS) is strongly preferred.
• Familiarity with regulatory frameworks, standards, and audits—e.g., SOC 2, ISO 27001, HIPAA, GDPR, FDA/CLIA, NIST.
• Knowledge of customer and third-party risk management best practices, including due diligence, contract review, and ongoing compliance monitoring.
• Experience establishing or maturing security review protocols, risk assessment workflows, or RFP automation/response tools (e.g., RFPIO, Loopio, Archer, MetricStream, or similar).
• Strong interpersonal and stakeholder management skills, with a track record of influencing decision-makers across business units.
• Excellent written and verbal communication skills—able to translate technical or risk/security topics into clear, actionable messaging for varied audiences.
• Self-driven, detail-oriented, and proactive in problem identification and resolution.
• Adaptable and resilient in fast-paced, ambiguous, high-stakes environments.
• Proven experience engaging directly with customers during RFP or diligence processes is strongly preferred.
• Experience working in regulated or heavily audited industries (e.g., life sciences, healthcare, SaaS, or finance).

Expected full time annual base pay scale for this position is $142K-$189K. Actual base pay will consider skills, experience and location.

Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time. In addition, GRAIL offers a competitive benefit package, including flexible time-off, a 401(k) with a company % match, medical, dental, and vision insurance plans, and carefully selected mindfulness offerings, in accordance with our applicable plans and policies. 

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. It is GRAIL policy to provide equal employment opportunities without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, marital status, protected veteran status, disability status, medical condition, or any other class or characteristic protected by applicable federal, state, and local laws. This policy applies to all phases of employment, including, but not limited to: recruiting, hiring, training, promotion, and termination at all levels of employment. GRAIL maintains a drug-free workplace.

Additionally, GRAIL will consider all qualified job-seekers with criminal histories in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us at [email protected] if you require an accommodation to apply for an open position.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

We welcome job-seekers from all backgrounds to join us!