The Senior Scientist I, Chemistry, will work in the drug discovery team to enhance the company pipeline of drugs to treat human diseases. The successful candidate will be an experienced PhD chemist/medicinal chemist with 1+ years of experience in the pharmaceutical or biotech industry. This position will report to the Principal Investigator (Chemistry) and is located in our state-of-the-art research facility near the University of Kansas in Lawrence, Kansas.
What You’ll Do:
• Contribute scientifically and intellectually to Deciphera kinase inhibitor discovery programs especially in the area of medicinal chemistry
• Design and implement synthetic routes to prepare proprietary small molecules for biological testing in assigned projects
• Track structure activity relationships and optimizing potency, selectivity, and pharmaceutical properties of small molecules for research programs
• Manage interdisciplinary engagement with others in the organization and with various CROs in the areas of kinase inhibitor switch control technology, structure-based drug design, kinase biochemistry, kinase cellular biology, and pharmacology/pharmaceutics
• Generate reports and presentations as required by the organization, and providing input on intellectual property activities
• Adhere to corporate policies including safety, FDA compliance and regulatory matters
• Values other people and promotes the welfare of the organization and colleagues
• Ph.D. in organic or medicinal chemistry with 1+ years of industrial or post-doctoral experience in synthetic organic chemistry / drug discovery or equivalent experience
• High level of creativity and productivity with strong synthetic chemistry problem solving skills
• Demonstrated excellence in organic synthesis, conversant with the current literature
• In-depth knowledge and hands-on experience with a wide range of techniques in synthesis, purification, and spectroscopic characterization of novel compounds (NMR, LC-MS, HPLC, etc.)
• Experience using the concepts and tools of structure-based drug design
• Excellent oral and written communication skills
• Proven interpersonal skills with the ability to work collaboratively as a member of cross-functional team and maintain effective working relationships
• Effective oral and scientific/technical writing communication skills
• Demonstrated proficiency using MS Office applications is required
Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $107,000 - $148,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.
Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)
Benefits:
Apply Now: Join us in our mission to improve the lives of people with cancer. Apply today to become a part of our dynamic team!
EQUAL EMPLOYMENT OPPORTUNITY INFORMATION
Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.
If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.
Experienced oncology marketer needed to lead brand marketing initiatives within Deciphera's expanding rare disease commercial team.
Bristol Myers Squibb is seeking a Clinical Science Lead to provide scientific leadership and oversight for neuroscience clinical trials, driving impactful patient-centered research.
AbbVie seeks a motivated Associate Scientist to advance late-stage organic chemistry process development in a collaborative pharmaceutical environment.
Seeking a Senior Antenna and RF Research Engineer with expertise in active phased array antennas to advance CesiumAstro’s satellite communication technologies.
Seeking a Core Model Engineer to develop and deploy AI-driven models for enterprise network infrastructure at Meter, a pioneering company in frontier AI and networking.
Advance neurological disease treatment as a Senior Scientist using machine learning and multi-omics data integration at AbbVie's Cambridge neuroscience team.
Contribute to pioneering mRNA vaccine development at Sanofi as a Winter-Spring 2026 Analytical Science Biochemistry Co-op in Waltham, MA.
A leading life sciences company seeks an experienced Biochemist Group Leader to perform advanced biochemical analyses and support team leadership in Cambridge, MA.
OpenAI is seeking a Research Engineer, Privacy, to develop cutting-edge privacy-preserving machine learning algorithms and ensure robust data protection in their AI products.
Dynamic Scientist role at GSK's Cambridge Structural Biology Center to advance cryo-EM based vaccine and medicine discovery.
Senior AI/ML Engineer needed at Abbott to develop and operationalize advanced machine learning and big data features in cardiac rhythm management devices and cloud platforms.
Excelsior Sciences is looking for a skilled High Throughput Screening Scientist experienced in automation and small molecule profiling to join their New York laboratory team.
Lead clinical laboratory services as Manager, ensuring operational excellence and quality patient care in Monterey Park.
Eurofins Scientific is looking for a Scientist I to perform microbiology testing and uphold GMP/GLP standards in their Lancaster, PA laboratory.
Passion. Commitment. Culture. At Deciphera, we are committed to improving the lives of people living with cancer. That passion for making a difference extends to the patient groups and communities in which we live and work. We recognize the value...
12 jobs