Full Stack Web Application Engineer

Leads the design, development, and deployment of scalable software solutions for NGS data processing. This role involves building full-stack applications for hybrid local/cloud environments, integrating job and task management systems and supporting regulated clinical lab operations. The engineer will also ensure compliance with ISO 13485 and Class III medical device software standards, while collaborating with globally distributed development teams.

Key Responsibilities:

– Design, develop, and maintain full-stack web applications using Python (Django, Flask, Celery), React, HTML/CSS, and JavaScript for deployment in local and AWS environments

– Build hybrid compute platforms for bioinformatics workflows supporting both local and cloud cluster modes, with a unified code base for clinical applications

– Continuously improve UI/UX, perform bug fixes, and implement automated unit and integration testing

– Set up and maintain CI/CD pipelines using Bamboo and Jenkins, manage deployments with Docker and virtual machines

– Utilize AWS (EC2, ECS, EFS, RDS) to ensure high performance, scalability, and cost-effectiveness

– Collaborate cross-functionally with international software teams via Jira, Bitbucket, and Confluence

– Translate scientific and clinical requirements into secure, compliant software systems aligned with ISO 13485 and IEC 62304 standards

Requires:

– Knowledge of ISO 13485-compliant software lifecycle processes and Class III medical device regulations, including software verification, validation, and traceability

– Familiarity with NGS data formats (FASTQ, BAM, VCF) and clinical laboratory workflows

– Working knowledge of containerization, automated testing, CI/CD implementation, and version control

– Experience with global development teams

EDUCATION/EXPERIENCE REQUIRED:

Masters Degree in Computer Science, Computer Systems Engineering, or a related field. Foreign degrees accepted plus 2 years’ experience as a software engineer or computer programmer, including full-stack development with Django, React, SQL/PostgreSQL, and cloud platforms (AWS)

WORK CONDITIONS:

This is a full-time, on-site role based in Natick, MA. Core hours are 9am to 6pm Monday through Friday. Availability for after-hours calls with international teams is required.

Pillar Biosciences is an Equal Opportunity and Affirmative Action employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; religion; age; nationality; marital status; sexual orientation; disability or any other characteristic protected by law.