Let’s get started
By clicking ‘Next’, I agree to the Terms of Service
and Privacy Policy, and consent to receive emails from Rise
Jobs / Job page
Principal AI Engineer image - Rise Careers
Job details

Principal AI Engineer

InsightRx is a pioneer in precision medicine, leveraging AI to optimize drug development and patient care. They seek a Principal AI Engineer to lead the design and development of advanced agentic AI systems and production-grade large language model applications, focusing on impactful healthcare technology.

Skills

  • Advanced prompt engineering and productionalization of LLM prompts
  • Deep understanding of agentic AI design patterns and orchestration
  • Experience deploying and maintaining production-grade LLM systems
  • Expertise in modern Python and asynchronous programming ecosystems
  • Familiarity with AI frameworks such as LangGraph or PydanticAI
  • Knowledge of foundation models including Claude and GPT-4
  • Strong grasp of distributed systems including queuing and asynchronous task handling

Responsibilities

  • Architect and design complex agentic AI systems tailored to healthcare and life sciences needs
  • Lead prompt engineering initiatives and develop advanced production-level prompting strategies
  • Guide model selection, deployment, optimization and ensure AI system reliability and performance
  • Build and maintain production-grade LLM applications using modern Python frameworks and asynchronous systems
  • Develop fault-tolerant AI infrastructure with robust queuing and error handling
  • Mentor engineers and collaborate cross-functionally to translate business objectives into scalable AI solutions
  • Drive adoption of modern agentic AI frameworks and contribute to strategic AI roadmap planning

Education

  • Bachelor’s degree in Computer Science, Machine Learning, or related field or equivalent practical experience

Benefits

  • Opportunity to work at the forefront of AI in healthcare and medicine
  • Engage in impactful projects improving patient outcomes and drug development
  • Collaborative and fast-paced technical environment
  • Career growth through leadership and mentorship roles
  • Access to cutting-edge AI technologies and frameworks
To read the complete job description, please click on the ‘Apply’ button

Average salary estimate

$195000 / YEARLY (est.)
min
max
$160000K
$230000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

Similar Jobs

Lead a team and manage technical projects at General Dynamics Mission Systems to drive innovation and mission success.

Photo of the Rise User
Posted 11 hours ago
Inclusive & Diverse
Rise from Within
Mission Driven
Diversity of Opinions
Work/Life Harmony
Take Risks
Collaboration over Competition
Growth & Learning
Transparent & Candid
Customer-Centric
Social Impact Driven
Rapid Growth
Passion for Exploration
Dare to be Different
Reward & Recognition
Friends Outside of Work
Medical Insurance
Dental Insurance
Vision Insurance
Mental Health Resources
Life insurance
Disability Insurance
Health Savings Account (HSA)
Flexible Spending Account (FSA)
Conferences Stipend
Bias Training
Employee Resource Groups
401K Matching
Paternity Leave
Maternity Leave
Some Meals Provided
Social Gatherings

Innovate and lead power protection designs for global data centers at a top tech company shaping the future of infrastructure.

Photo of the Rise User
Venture Global LNG Hybrid Houston, Texas, United States
Posted 11 hours ago

Experienced Structural Designer needed at Venture Global LNG to lead design teams and innovate modeling techniques for large-scale petrochemical and LNG projects.

Photo of the Rise User
Anduril Industries Hybrid Mountain View, California, United States
Posted 17 hours ago

Drive supplier production excellence as a Supplier Industrialization Engineer at Anduril Industries, advancing critical PCB/PCBA manufacturing for defense technology.

Photo of the Rise User
Terabase Energy Hybrid No location specified
Posted 8 hours ago

Mechanical Engineer needed at Terabase Energy to design and innovate mechanical solutions that accelerate large-scale solar energy deployment.

Photo of the Rise User

Contribute technical expertise as an Application Engineer supporting 3M’s aerospace adhesive and sealant technologies in Maplewood, MN.

Photo of the Rise User
Posted 8 hours ago

Drive innovation and scalability as a Senior Platform Engineer at Mambu, building secure and efficient cloud infrastructure for the future of fintech.

Photo of the Rise User

Contribute to electric aviation innovation as a Systems Engineer focused on ARP 4754A-compliant avionics system development and certification at BETA Technologies.

Photo of the Rise User
SYNNEX Hybrid Fremont, California, United States
Posted 9 hours ago

Seeking a motivated Software DevOps Engineer to design and maintain infrastructure and automation for Hyve Solutions’ large-scale test platforms.

Serco North America Hybrid CO-Colorado Springs US-CO US-CO-Air Force Academy US-CO-Centennial US-CO-Fort Carson US-CO-Peterson AFB US-CO-Schriever AFB
Posted 3 hours ago

Lead satellite safety and laser system analysis efforts with Serco in support of critical U.S. Space Command operations in Colorado Springs.

Posted 14 hours ago

SmartNews is hiring an Engineering Manager to lead and contribute to a cutting-edge news application team in Palo Alto, blending technical leadership with hands-on development.

Oura Hybrid No location specified
Posted 9 hours ago

Lead and manage Oura's US Site Reliability Engineering team to build scalable, compliant AWS cloud infrastructure supporting enterprise customers.

Photo of the Rise User
Posted 15 hours ago

Experienced data infrastructure engineer needed to lead database reliability and scalability initiatives at Calendly in a remote US-based role.

MATCH
Calculating your matching score...
FUNDING
DEPARTMENTS
SENIORITY LEVEL REQUIREMENT
TEAM SIZE
No info
HQ LOCATION
No info
SALARY RANGE
$160,000/yr - $230,000/yr
EMPLOYMENT TYPE
Full-time, unknown
DATE POSTED
July 26, 2025
Risa star 🔮 Hi, I'm Risa! Your AI
Career Copilot
Want to see a list of jobs tailored to
you, just ask me below!