Senior Director, Product Communications

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.

As a leader in precision health, Guardant Health is committed to transforming cancer care through innovative diagnostics and data-driven solutions. The Sr. Director of Product Communications is a strategic leadership role responsible for shaping and executing the communication strategy for Guardant’s portfolio of products — from development through launch and lifecycle management.

This individual will drive storytelling that highlights the impact of our products on patients, providers, and the healthcare system, while helping internal and external stakeholders understand the science, innovation, and value behind our offerings. This role is critical to building a consistent and compelling narrative around Guardant’s products across diverse audiences — including customers, employees, media, and industry influencers.

Key Responsibilities:

Strategy & Leadership

• Define and lead the communications strategy for Guardant’s product portfolio, spanning early development through launch and lifecycle updates.

• Serve as a trusted advisor to product, oncology, and executive leadership teams on messaging, media strategy, and visibility opportunities.

• Establish clear KPIs to measure impact and continuously evolve strategy based on insights and outcomes.

Storytelling & Messaging

• Translate complex scientific, technical, and clinical concepts into clear, compelling narratives tailored for diverse audiences—patients, providers, investors, employees, media, and industry influencers.

• Develop core product positioning that highlights innovation, value, and patient impact across channels.

• Ensure consistency and clarity of voice across all product communications.

Stakeholder Engagement & Collaboration

• Partner with Marketing, Medical Affairs, Technology, Commercial, Regulatory Affairs, and Public Affairs to align messaging across the product portfolio.

• Collaborate with Internal Communications and People teams to engage employees and connect them to product milestones.

• Build strong relationships with external agencies, media, and industry partners to amplify Guardant’s leadership story.

Execution & Content Development

• Oversee multi-channel content creation, including press releases, web content, FAQs, social media, video, and thought leadership assets.

• Lead communication planning for key product milestones such as launches, clinical trial readouts, regulatory approvals, and partnerships.

• Manage agency partners, communications budgets, and internal resources to deliver high-impact, timely results.

Market Awareness

• Monitor competitive activity, market dynamics, and industry events to proactively identify opportunities to strengthen Guardant’s reputation.

• Bachelor’s degree in Communications, Marketing, Journalism, Life Sciences, or related field; advanced degree preferred.
• 15+ years of experience in corporate or product communications, preferably within healthcare, biotech, diagnostics, or medical technology.
• Deep experience leading communications strategy for scientific or healthcare products — with an expertise in oncology preferred.
• Strong grasp of healthcare industry dynamics and ability to navigate communications around clinical data, regulatory milestones, value, and patient impact.
• Proven ability to partner with senior executives and cross-functional leaders to shape strategy and influence decision-making.
• Exceptional storytelling, writing, and editing skills, with the ability to adapt tone and messaging across audiences and platforms.
• Experience with issues management, media relations, and executive communications.
• Confident, collaborative leader with a track record of managing and mentoring teams.
• Strategic thinker who is proactive, agile, and solutions-oriented in a fast-paced, innovative environment.

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Hybrid Work Model: At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The US base salary range for this full-time position is $180,630 to $248,330. The range does not include benefits, and if applicable, bonus, commission, or equity. The range displayed reflects the minimum and maximum target for new hire salaries across all US locations for the posted role with the exception of any locations specifically referenced below (if any).

For positions based in Palo Alto, CA or Redwood City, CA, the base salary range for this full-time position is $212,500 to $292,150 . The range does not include benefits, and if applicable, bonus, commission, or equity.

Within the range, individual pay is determined by work location and additional factors, including, but not limited to, job-related skills, experience, and relevant education or training. If you are selected to move forward, the recruiting team will provide details specific to the factors above.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to [email protected]

A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

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Please visit our career page at: http://www.guardanthealth.com/jobs/