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IT Portfolio Manager - job 1 of 2

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

Summary

GeneDx, a patient-centered technology company, is seeking an IT Portfolio Manager who will play a pivotal role in shaping our IT programs, projects, and products to drive successful outcomes across the organization. In this strategic role, you will be responsible for the centralized management of IT portfolios of at least 2 IT teams, ensuring alignment of IT initiatives with business strategies, optimizing resource allocation, and delivering projects within scope, budget, and timeline constraints. As the key liaison between the IT department and other business units, you will facilitate communication, drive best practices, and ensure that IT investments deliver maximum value

Job Responsibilities

  • Execute the portfolio strategy for a diverse range of IT programs, projects and products, aligning with organizational goals.
  • Manage the success of the development process, ensuring that all programs meet both business objectives and user needs.
  • Develop, implement, and continuously improve portfolio management processes and best practices for your assigned team.
  • Work closely with cross-functional teams to help prioritize features, assist in development of roadmaps, and gather customer feedback for ongoing enhancement.
  • Collaborate closely with IT engineering teams to contribute to the technical implementation of product features, ensuring alignment with overall product vision and user needs.
  • Utilize productivity tools like Jira/Confluence, Monday.com and Smartsheets, ServiceNow to effectively track tasks, progress, and milestones.
  • Drive enhancements in service delivery and streamline IT operations to elevate the overall user experience through completion of projects.
  • Other special initiatives as assigned.

People Manager

  • No

 Education, Experience, and Skills

  • Bachelor’s Degree: A degree in a technical or scientific field is required.
  • 2-4 years of experience in project, product or portfolio management, ideally within IT service management (ITSM) in a SaaS environment with the ability to translate technical requirements into actionable product features.
  • Self-starter with exceptional organizational skills, capable of effectively managing and prioritizing multiple programs.
  • Collaborative team player with a customer-focused mindset and strong technical troubleshooting abilities.
  • Skilled at navigating ambiguity, scoping MVPs, and aligning team execution with broader platform goals.
  • Skilled at guiding users and stakeholders to make informed decisions that align with project goals.
  • Experience in creating project product artifcats and training users on new product implementations.
  • Strong communicator with the ability to convey technical issues and solutions clearly across various organizational levels.
  • Familiarity with HIPAA, CLIA, SOX, SOC2 and/or HITRUST compliance standards.

 

Certificates, Licenses, Registrations

 Associate Product, Project, or Program Manager Certification is preferred; candidates without this certification are expected to obtain it within six months of hire.

Physical Demands

  • Example: Ability to stand, walk, and sit for extended periods during program launches.

Work Environment

  • Work is primarily performed in a remote environment with some travel to Gaithersburg lab as needed.
  • Standard work hours are Monday through Friday, 9 AM to 5 PM EST, with occasional Afterhours or weekends required during launch of programs.

 

 

#LI-REMOTE

 

 

 

Pay Transparency, Budgeted Range
$95,658$127,544 USD

~

Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most. 

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

  • High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
  • Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

  • Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
  • Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
  • Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:  

  • Be bold in our vision & brave in our execution. 
  • Communicate directly, with empathy. 
  • Do what we say we're going to do.  
  • Be adaptable to change.  
  • Operate with a bias for action.    

Benefits include:

  • Paid Time Off (PTO)
  • Health, Dental, Vision and Life insurance
  • 401k Retirement Savings Plan
  • Employee Discounts
  • Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.

Average salary estimate

$111601 / YEARLY (est.)
min
max
$95658K
$127544K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

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At GeneDx, we believe that everyone deserves personalized, targeted medical care—and that it all begins with a genetic diagnosis

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Full-time, remote
DATE POSTED
August 14, 2025
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