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Principal IS Bus Sys Analyst

Career Category

Information Systems

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Principal IS Bus Sys Analyst 

What you will do and what we expect of you

Let’s do this. Let’s change the world. In this vital role you will:  

 Duties: Serve as a client facing partner and / or technical product owner working with business and DTI team members to implement and support Generative AI and Structured Content Management/Authoring initiatives; Process and systems analysis, requirements elicitation, articulating system solutions and approaches for addressing business needs; Collaborate closely with business partners to evaluate and adopt innovative AI and ML technologies to address business needs; Contribute to shaping the vision and roadmap for the GRAAS software ecosystem; Developments in AI/ML and their applications in pharmaceutical industry; Adhere to DTI standards including Agile scrum teams, release trains, and following GxP Quality and SDLC processes; Identify business problems or management objectives that can be addressed through data analysis; Read scientific articles, conference papers, or other sources of research to identify emerging analytic trends and technologies; Recommend data-driven solutions to key stakeholders; and Test, validate, and reformulate models to ensure accurate prediction of outcomes of interest. May telecommute. Position requires 5% of travel to various unanticipated worksites nationally and internationally. 

Requirements: Master’s degree (or foreign equivalent) in Business Analytics and Information Systems, Engineering or related field and 6 years of experience in the following: 

Large Language Models (LLMs), including developing conversational AI systems such as chatbots using technologies including NLP, LLM & AI to enhance process efficiency and user engagement;  AWS services including EC2 and S3;  Python and SQL for performing advanced data analysis;  Conducting process and systems analysis, gathering and documenting requirements, and translating business needs into technical specifications to drive the successful implementation of AI and ML projects;  Articulating and presenting system solutions and approaches to stakeholders, ensuring alignment with business objectives and facilitating the adoption of AI and ML technologies to address critical business challenges;  Working with Agile Scrum methodologies, participating in release trains, and adhering to validated quality processes and SDLC standards; and  Exploring emerging AI/ML trends, evaluating technologies such as Large Language Models (LLMs), and recommending innovative solutions to solve complex business challenges. 

 
Contact: Interested candidates please apply via https://careers.amgen.com/en/search-jobs and search for job # R-222026. 

Job type: Full Time position. The annual salary range for this position in the U.S. is $144,272.00 - $171,506.00 per year. Also, this position offers stock, retirement, medical, life and disability insurance and eligibility for an annual bonus or for sales roles, other incentive compensation. For more details visit https://careers.amgen.com/life-at-amgen/benefits/ 

 What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

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Average salary estimate

$157889 / YEARLY (est.)
min
max
$144272K
$171506K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

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To serve patients. Amgen strives to serve patients by transforming the promise of science and biotechnology into therapies that have the power to restore health or save lives. In everything we do, we aim to fulfill our mission to serve patients....

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Full-time, hybrid
DATE POSTED
August 11, 2025
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