Director of Observational Research, Pharmacovigilance Epidemiology and Causal Inference

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Director of Observational Research, Pharmacovigilance Epidemiology and Causal Inference

What you will do

Let’s do this. Let’s change the world. In this vital role you will lead a Pharmacovigilance Epidemiology and Causal Inference team within the Data and Analytics Center (DAC). A CfOR director is recognized as a strong scientific contributor and is a first or contributing author for papers in peer-reviewed journals or for internal reports that enhance the company’s mission. This role will primarily be located on the Amgen corporate campus in Thousand Oaks, CA, but remote opportunities may also be available.

The team consists of 6+ epidemiologists and works collaboratively across therapeutic areas to design and implement studies using real-world data to inform questions related to product safety and effectiveness. Responsibilities range from estimating exposure to Amgen medicines across countries, estimating background rates of events to inform signal evaluations, conducting post-approval safety studies globally (including post-marketing requirements, commitments, and post-authorization safety studies) to evaluate the benefit-risk balance of Amgen therapies, and conducting studies requiring advanced causal inference methodologies including real-world comparative effectiveness. The team is also responsible for developing and optimizing analytic tools to enable the delivery of high-quality, principled, and state of the art research efficiently for the organization. In addition to managing and coordinating this work, the Director will also serve on the Extended Leadership Team (ELT) of the department and actively engage in efforts around department strategy, prioritization, and talent and culture. Additionally, the Director will work cross-functionally with Global Patient Safety and Global Regulatory Affairs and Strategy at the leadership level to optimize the use of real-world evidence to inform patient benefit-risk and regulatory decision making.

• Effectively leads, develops, and mentors a team of scientists
• Design and execute studies to support evidence generation such as identifying appropriate patient populations, assessing disease burden and resource utilization, obtaining product registrations and label-expansions, meeting post-marketing requirements/commitments, and product differentiation
• Find opportunities to substitute for and/or complement interventional studies to reduce time and cost of drug development
• Influence cross-functional team members as to the appropriate use and timing of non-interventional research to answer high-priority strategic business questions
• Leverage real-world data and CfOR analytic approaches to inform high-value business decisions for multiple stakeholders
• Track business and functional priorities and align resources against those priorities
• Contribute to the mission of CfOR, including progressing innovative epidemiological methods and analytical capabilities to support CfOR’s leadership role within Amgen and industry
• Participate in initiatives to improve capabilities within CfOR and provide input into CfOR meetings
• Contribute to the development of product and CfOR strategies
• Develop and maintain relationships with key leaders in observational research

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 4 years of scientific experience

OR

Master’s degree and 8 years of scientific experience

OR

Bachelor’s degree and 10 years of scientific experience

In addition to meeting at least one of the above requirements, you must have at least 4 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications:

• Doctorate in Epidemiology or other subject with high observational research content

• Experience in the design, execution, and analysis of observational research studies within Pharmaceutical or Public Health setting

• Experience in research to support drug development

• Experience in observational research project planning and management

• Excellent verbal and writing communication and interpersonal skills

• Experience working in multi-disciplinary teams

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range