Scientist--ADC Biology (non PhD)
Use Your Power for Purpose
At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. Your work will have a profound impact on improving patients' lives globally. Whether you are involved in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will leverage cutting-edge design and process development capabilities to accelerate and deliver best-in-class medicines to patients worldwide.
ROLE SUMMARY
As a Scientist (non-PhD) on our ADC Biology team, you will be a key driver in advancing the next-generation ADC technologies through collaborative, cross-functional research that spans early discovery to pre-clinical development. You will develop assays and execute screening and identification of novel chemotypes that function as payloads for antibody drug conjugates for cancer therapy. You will work collaboratively with chemistry and other cross functional teams to understand mechanism of action of identified payloads. You will analyze, interpret and communicate the data effectively to key stake holders.
KEY RESPONSIBILITIES
Apply cellular, biochemical, immunological, and molecular biology laboratory techniques to preclinical research projects in the areas of Cancer signaling and Cancer biology
Investigate MOAs of our therapeutics through development, optimization, and execution of complex assays
Interact and collaborate with other functional groups across research
Provide leadership within technical area of expertise; may train, direct or mentor others
Design and execute key experiments to investigate novel therapeutic targets and MOAs of novel payloads to enable clear go/no-go decisions.
Independently analyze data, document results, and present findings to large and small audiences
Maintain rigorous records of experimental progress using electronic laboratory notebooks
Present experimental results and scientific rationale to colleagues
Execute molecular, biochemcial and cell-based methodologies including cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescent and live cell microscopy.
Aid in execution and analysis of additional experiments as need arises within the ADC discovery research team
MINIMUM REQUIREMENTS
Bachelor's degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field and 6+ years' relevant industry ADC Biology or small molecule experience OR
M.S. degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field with 4+ years' relevant industry ADC Biology or small molecule experience
Experience with Microsoft Office (Excel, Word, PowerPoint) and analytical software programs (e.g., Prism, FlowJo)
Experience designing, performing and interpreting complex experiments that require significant insight into problems being addressed with some guidance
Working knowledge of the Cancer Biology and Cancer therapeutics areas, especially small molecule agents, Biologics and ADCs
Experience working independently and working on multiple projects
Experience collaborating across teams and a variety of disciplines to provide experimental expertise and support others on joint projects
Experience leading parts of projects or initiatives within area of expertise
Excellent written/oral communication skills with experience presenting/sharing details of the work with key stakeholders
PREFERRED REQUIREMENTS
Experience in experimental cancer biology, biochemical and/or immunological techniques (e.g., Cell culture, cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescent and live cell microscopy.).
Background knowledge in the field of cell signaling and biochemistry
Experience developing complex cell and biochemical assays
PHYSICAL/MENTAL REQUIREMENTS
Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis
Must be able to wear specialized protective clothing and PPE (e.g., lab coat, safety shoes/glasses)
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Majority of work will be performed during the standard workday, but ability to work flexible hours when needed is preferrable
Work Location Assignment: On Premise
Relocation support may be available
The annual base salary for this position ranges from $77,100.00 to $128,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Average salary estimate
If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.
Pfizer seeks a Customer Service Representative I in Collegeville to manage vaccine and hemophilia customer inquiries, orders, and logistics coordination at its call center.
Pfizer Dermatology is hiring a field-based Regional Brand Activation Director to lead regional marketing execution, drive brand visibility, and collaborate cross-functionally to support product launches and market growth across the region.
Senior Research Scientist role to advance secure parsers, MBSE tools, and open-architecture security technologies for DoD customers while leading proposals and business development.
Novartis seeks an experienced Veterinary Investigative Pathologist to lead preclinical pathology and translational efforts supporting novel drug discovery and development.
Experienced oncology physician needed to lead medical monitoring and clinical development activities for late-stage PD-1/VEGF bispecific trials at Pfizer's Bothell site.
Join LLNL’s NIF Target Diagnostics team to design, test, and analyze advanced diagnostic instruments and contribute to high-energy-density experiments and system improvements.
Support e.l.f. Beauty's Product Development team with brief creation, sample management, formula tracking, and trend research to help bring new color cosmetics and skincare innovations to market.
Evonik is seeking an Applications Scientist to drive coating formulation, testing, and application development that improves performance and sustainability for industrial and automotive customers.
An experienced nonclinical regulatory toxicologist is needed to lead cross-functional safety strategy and regulatory interactions for immunology therapeutic projects at Novartis.
Work as a hands-on Formulations Scientist at Eurofins PSS in Boston, performing formulation and analytical characterization of biologics, nucleic acids, and lipid nanoparticles using HPLC, AKTA, DLS and related wet-lab techniques.
Lead the hardware–software co-design and control of a bimanual robot platform to advance dynamic manipulation and human-cadence movement in a Cambridge-based robotics research team.
Join Asimov’s cell line development team to drive CHO-based engineering and workflow innovation for next-generation biologic therapeutics in a hybrid Boston lab environment.
Lead Aidoc's clinical research efforts to design, execute, and publish high-quality studies that validate AI-enabled medical solutions and accelerate market adoption across the U.S.
Breakthroughs that change patients' lives.
48 jobs
🔮
Hi, I'm Risa! Your AI Career Copilot
you, just ask me below!
