Principal Cleaning Validation Engineer

Use Your Power for Purpose

At Pfizer, we believe that every role contributes to our mission of improving patients' lives. Whether you are involved in the design and development of manufacturing processes for products or supporting the upkeep of systems, engineering is crucial to ensuring customers and patients receive the medicines they need. By collaborating with our forward-thinking engineering team, you'll play a pivotal role in accelerating the delivery of medicines to the world.

What You Will Achieve

The Principal Cleaning Validation Engineer is a team leader role responsible for major aspects of the site validation program and reports to the Site Technical Services Technical Programs manager. This role provides leadership and technical support and leadership in clean validation area and laboratory oversight. Specific areas of responsibility include cleaning chemistry, mixing of process solutions, process solution expiry, and program improvements within a cGMP biopharmaceutical manufacturing facility. The incumbent is responsible for delivering overall site cleaning validation program effectiveness and compliance in partnership with validation program owners across Andover site functions and the Pfizer network.

In this role, you will:

• Develop and co-lead innovative projects across the operating unit, ensuring timely communication with key stakeholders on source changes, technical transfers, and Cost Improvement Projects.

• Manage project plans, timelines, resources, and address time constraints and scheduling conflicts.

• Implement appropriate process control strategies across unit operations, including trending, review, and action plans as needed.

• Drive alignment across stakeholders on technical strategies and priorities identified in the Technology Lifecycle Plan.

• Provide leadership and technical support of the site cleaning program, including cleaning chemistry, cleaning validation, and the cleaning program master plan.

• Site Cleaning Program owner and expert for cleaning validation.

• Team leader responsible for the safety and oversight of Technical Programs laboratory-based and at-scale work, including small-scale cleaning validation program requirements, mixing qualification, and solution chemical stability and expiry.

• Utilize Quality Risk Management to proactively manage risks including compliance, equipment, and systems to consistently and reliably meet cleaning program requirements.

• Provide support for manufacturing investigations related to the cleaning program.

• Collaborate and contribute to overall process improvements within a cGMP biopharmaceutical manufacturing facility.

• The Principal Cleaning Validation Engineer is a member of the Andover STS Technical Programs team

Here Is What You Need (Minimum Requirements)

•  Applicant must have a bachelor's degree with at least 4 years of
  experience; OR a master's degree with at least 2 years of experience; OR
  a PhD with 0+ years of experience; OR as associate's degree with 8 years
  of experience; OR a high school diploma (or equivalent) and 10 years of
  relevant experience 

• Pharmaceutical/biopharmaceutical industry experience

• Biotechnology industry experience

• Effective written and verbal communication skills

• Strong interpersonal skills and the ability to work collaboratively in a team environment across various business functions

• Experience in project management and leading complex projects

• Ability to develop and manage plans to achieve objectives

Bonus Points If You Have (Preferred Requirements)

• Relevant cleaning validation experience

• Experience developing philosophies/approaches for or managing cleaning validation programs applicable to the manufacture of biopharmaceutical drug substance, drug product, or medical device

• Experience or broad knowledge in biopharmaceutical development, manufacturing, and lifecycle management

• Active participation in industrial/professional organization focused on advancing biopharmaceutical development, manufacturing, regulatory practices

• Demonstrated leadership in a matrix organization

• Strong leadership and team management skills

• Excellent analytical and strategic thinking abilities

• Ability to influence and drive alignment across stakeholders

  
 

PHYSICAL/MENTAL REQUIREMENTS

Ability to perform mathematical calculations, scientific computation, complex data analysis, verbal communication, written communication

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Occasional domestic and international travels

• Occasional off-hour support to address time-sensitive production and business-related issues

Other Job Details:

• Last day to Apply: August 13th, 2025

• Work Location Assignment: Hybrid

The annual base salary for this position ranges from $112,700.00 to $187,800.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Engineering