Associate Obesity Research Scientist

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) of Eli Lilly and Company focuses on the discovery of biologic, small molecule, and genetic therapeutics for the treatment of diabetes, obesity, and associated complications.

We are seeking a skilled and motivated individual who can help build a highly collaborative, successful drug discovery and development team in the Obesity research group in Boston. A successful candidate will use their strong in vivo pharmacology background and complementary laboratory and/or in vitro skills to play a critical role in supporting discovery efforts and established pipeline projects with an emphasis on anti-obesity therapeutics. You will be responsible for setting up critical capabilities in the laboratory setting and working with other scientists within and across departments to achieve project and department goals.

Key Responsibilities:

• Plan and independently implement in vivo experiments to support preclinical characterization and evaluation of targets/pathways that regulate energy balance.
• Perform routine rodent handling, dosing, and small animal surgeries, including but not limited to parenteral routes of administration.
• Perform molecular and biochemical assessments on ex vivo samples in collaboration with colleagues in other departments.
• Function independently, work within a team-oriented lab environment, and work within cross-functional project teams.
• Maintain accurate record-keeping, perform independent data analysis, and report data in written and oral formats.
• Ensure full compliance with Lilly Research Policies and complete all required training activities within the specified timeframe.

Minimum Qualifications:

B.S. and/or M.S. in biology or a closely related field with 4+ years of experience

Additional Skills/Preferences:

• A background in the biology and physiology of energy balance regulation and metabolic disease – relevant models of obesity 
• Experience with in situ hybridization, various assay detection technologies (fluorescence, luminescence, FRET, alpha-screen, ELISA assays), and the ability to implement and validate new assay technologies.
• Experience with imaging techniques and/or flow cytometry.
• Experience with assays to assess mitochondrial function including high-capacity respirometry 
• Experience in primary cell isolation and downstream cell line work, including functional, molecular, and screening assays
• Demonstrated ability to work on cross-functional teams and projects.
• Strong communication skills and experience presenting data in a team environment.

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Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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