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Manufacturing Equipment Engineer (E2/Sr)

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Senior Level:

You are the engineer Illumina is looking for.  In your future role at the Wisconsin site of the global leader in genetic sequencing, you will be one of a group of equipment engineers providing maintenance and technical support for the equipment and systems producing the enzymes that fuel Illumina’s sequencing and array-based solutions for analysis of genetic variation and function, in realms from cancer research to agriculture.  You will be part of a self-directed and diverse team that is responsible for all aspects of equipment maintenance (including corrective, preventative, and predictive) with the primary focus being on fermentation vessels. You will also regularly work with other teams and vendors in a collaborative environment.  We want your talent, genuine curiosity about applied science, commitment to creative problem solving, and drive to get things done


Responsibilities 

  • Works with diverse cross functional teams and third-party vendors to investigate, diagnose, repair, and document issues and breakdowns of equipment and systems including fermentation vessels, chromatography instruments, cold storage, centrifuges, and analytical equipment.

  • Main point of contact for end users and vendors for the maintenance and care of the fermentation vessels.

  • Works with diverse cross functional teams on projects to improve and develop processes/equipment using lean manufacturing and 6 Sigma methodologies

  • Provides analysis and recommendations for risk mitigation and process efficiencies for maintenance plans and activities

  • Ability to write, review, and manage equipment protocols, reports, and work instructions with a detailed orientated approach

  • Support of internal processes to ensure regulatory compliance is maintained

  • Generation of specifications and other engineering documents as used for equipment design and qualification

  • Collaborate with interdisciplinary teams locally, nationally, and internationally to exchange best practices, develop, or align processes, and complete projects

  • Mentors supporting engineers on technical skills in one’s areas of expertise

Minimum Requirements:

  • Excellent interpersonal skills and a demonstrated ability to work on diverse teams and learn quickly.  

  • B.S. degree in Engineering or equivalent technical training/experience

  • 5+ years relevant engineering/equipment maintenance experience.

Equipment Engineer 2 Level:

You are the engineer Illumina is looking for.  In your future role at the Wisconsin site of the global leader in genetic sequencing, you will be one of a group of equipment engineers providing maintenance and technical support for the equipment and systems producing the enzymes that fuel Illumina’s sequencing and array-based solutions for analysis of genetic variation and function, in realms from cancer research to agriculture.  You will be part of a self-directed and diverse team that is responsible for all aspects of equipment maintenance (including corrective, preventative, and predictive) with the primary focus being on fermentation vessels. You will also regularly work with other teams and vendors in a collaborative environment.  We want your talent, genuine curiosity about applied science, commitment to creative problem solving, and drive to get things done


Responsibilities 

  • Works with diverse cross functional teams and third-party vendors to investigate, diagnose, repair, and document issues and breakdowns of equipment and systems including fermentation vessels, chromatography instruments, cold storage, centrifuges, and analytical equipment.

  • Main point of contact for end users and vendors for the maintenance and care of the fermentation vessels.

  • Opportunities to work with diverse cross functional teams on projects to improve and develop processes/equipment using lean manufacturing and 6 Sigma methodologies

  • With vendor and team support, provide analysis and recommendations for risk mitigation and process efficiencies for maintenance plans and activities

  • Ability to write, review, and manage equipment protocols, reports, and work instructions with a detailed orientated approach

  • Support of internal processes to ensure regulatory compliance is maintained

  • With vendor and team support, generation of specifications and other engineering documents as used for equipment design and qualification

  • Opportunities to collaborate with interdisciplinary teams locally, nationally, and internationally to exchange best practices, develop, or align processes, and complete projects

Minimum Requirements:

  • Excellent interpersonal skills and a demonstrated ability to work on diverse teams and learn quickly.  

  • B.S. degree in Engineering or equivalent technical training/experience

  • 3+ years relevant engineering/equipment maintenance experience.

The estimated base salary range for the Manufacturing Equipment Engineer (E2/Sr) role based in the United States of America is: $89,400 - $134,000. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.


We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.
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Average salary estimate

$111700 / YEARLY (est.)
min
max
$89400K
$134000K

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To improve human health by unlocking the power of the genome.

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Full-time, onsite
DATE POSTED
August 6, 2025
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