Senior Scientist - job 1 of 2

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Job Profile:

We are seeking a highly motivated and enthusiastic scientist to join the Bioanalytical Research group within the Pharmaceutical Candidate Optimization (PCO) department in Lawrenceville, NJ. PCO is a multidisciplinary team with expertise in DMPK, toxicology, and pharmaceutics, dedicated to advancing novel drug discovery targets.

As part of our diverse analytical team, the successful candidate will contribute deep expertise in protein characterization and quantitation of protein targets and biomarkers in complex biological matrices. This role is ideal for a scientist with a strong background in protein/peptide mass spectrometry and data analysis, who is eager to apply innovative technologies and methodologies for protein identification and in vivo quantitation.

Our group has a proven track record in developing sensitive and selective LC-MS-based quantitative assays. Building on this foundation, the candidate will be expected to enhance our capabilities through advanced sample preparation techniques and mass spectrometric detection strategies. The goal is to define and implement optimal bioanalytical approaches that support and accelerate drug discovery programs.

Job Responsibilities:

The successful applicant will be primarily responsible for the following:

• Assay-development and quantification of targeted proteins in biological samples (plasma, tissue homogenates, etc.) using LC-MS and allied techniques, e.g., immunoprecipitation, SEC, Ion-exchange chromatography, SDS-PAGE.
• Expert operation of Orbitrap, Astral, Stellar, and Triple Quad mass spectrometers (Thermo, Sciex).
• Work in a team environment to integrate LC-MS, affinity technologies and multidimensional protein separation to differentiate and quantify drugs, metabolites, and protein biomarkers in biological matrices.
• Collaborate in a multidisciplinary research environment to address bioanalytical issues related to discovery programs and provide input into bioanalytical strategies.
• Represent the department on project teams and present data at internal department and / or othe company meetings as well as external conferences.
• Maintain good laboratory practices and documentation (ELN)

Job Requirements/Education:

• Ph.D. degree in analytical chemistry, biochemistry or protein science with 2-5 years of pharmaceutical or relevant industry experience, with emphasis on qualitative and quantitative protein analysis using mass spectrometry
• Experience with high resolution accurate mass analysis and proteomic-type experimentation strongly desired
• Experience with peptide mapping and molecular characterization of intact/subunit analysis of proteins using mass spectrometry
• Experience with mass spectrometry data analysis software (Proteome Discoverer, Protein Metrics, Spectronaut, Skyline, MaxQuant, DIANN)
• Experience with immunocapture and/or standard biochemical protein analysis (SDS-PAGE, Western-blot, microBCA, ELISA)
• Experience in protein conjugation techniques for reagent labelling and immobilization
• Ability to independently diagnose and solve complex technical and scientific problems
• Ability to troubleshoot and perform minor instrument repairs to maintain highest performance and minimize downtime
• Self-motivated with excellent communication and interpersonal skills.  Able to effectively manage and interface with others in a matrix team environment

#LI-Onsite

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. 

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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