Let’s get started
By clicking ‘Next’, I agree to the Terms of Service
and Privacy Policy, and consent to receive emails from Rise
Jobs / Job page
Principal Scientist, Machine Learning (Protein Design) image - Rise Careers
Job details

Principal Scientist, Machine Learning (Protein Design)

Ampersand Biomedicines is a cutting-edge biotechnology company specializing in multi-specific medicines and computational antibody design. They seek a Principal Scientist in Machine Learning with deep expertise in antibody binder design and protein engineering to lead the development of advanced machine learning frameworks.

Skills

  • Strong foundation in machine learning and deep learning techniques.
  • Expertise in sequence- and structure-based protein and antibody design.
  • Proficiency with protein design tools such as AlphaFold, ESM, ProteinMPNN, RF-Diffusion, Rosetta.
  • Advanced skills in Python programming and ML frameworks like PyTorch, TensorFlow, JAX.
  • Capability to develop novel AI and biomolecular design methods.

Responsibilities

  • Design and conduct independent machine learning research focused on antibody binder design.
  • Develop robust, production-quality models advancing antibody engineering and de novo design.
  • Collaborate closely with experimental teams to integrate computational and bench capabilities.
  • Communicate scientific insights effectively to leadership and cross-functional teams.
  • Manage and mentor the Machine Learning team contributing to the AND-Body platform.
  • Foster a collaborative, high-performing, and accountable team culture.
  • Drive alignment and collaboration with key stakeholders to ensure business success.

Education

  • PhD in biochemistry, biophysics, computational chemistry, computational biology, computer science, machine learning, or related computational disciplines applied to biological or chemical problems.

Benefits

  • Opportunity to work at a dynamic, innovative biotech company on cutting-edge antibody design.
  • Collaborative and entrepreneurial work environment.
  • Mentorship and clear career development pathways.
  • Being part of a team shaping next-generation biotherapeutics.
To read the complete job description, please click on the ‘Apply’ button

Average salary estimate

$185000 / YEARLY (est.)
min
max
$150000K
$220000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

Similar Jobs
Photo of the Rise User
Posted 23 hours ago

Drive cutting-edge analytical development of complex biotherapeutics using advanced mass spectrometry and chromatography at AbbVie's South San Francisco facility.

Photo of the Rise User

Lead spectroscopy and process analytical technology initiatives at 3M to support innovative R&D and manufacturing processes.

Photo of the Rise User
Posted 21 hours ago

Applied Machine Learning Scientist role at Unlearn to innovate AI solutions powering the future of medicine by forecasting patient outcomes using advanced machine learning techniques.

Photo of the Rise User

Eurofins Scientific is hiring an Associate Chemist for environmental testing on a 2nd shift schedule to perform GC/MS analysis and quality control.

xAI Hybrid Palo Alto, California, United States
Posted 16 hours ago

Drive the future of AI research and search as an AI Engineer & Researcher at xAI, operating from Palo Alto with a focus on RL training and evaluation benchmarks.

Alpen Labs Hybrid New York City; Remote
Posted 3 hours ago

Alpen Labs invites talented, Bitcoin-enthusiastic professionals to connect and explore impactful opportunities within their fully remote team driving innovative decentralized finance.

Photo of the Rise User
Posted 16 hours ago
Inclusive & Diverse
Mission Driven
Social Impact Driven
Passion for Exploration
Dare to be Different
Diversity of Opinions
Reward & Recognition
Empathetic
Feedback Forward
Work/Life Harmony
Collaboration over Competition
Growth & Learning
Transparent & Candid
Customer-Centric
Rise from Within
Friends Outside of Work
Medical Insurance
Dental Insurance
Vision Insurance
Mental Health Resources
Life insurance
Disability Insurance
Health Savings Account (HSA)
Flexible Spending Account (FSA)
Learning & Development
Work Visa Sponsorship
Employee Resource Groups
401K Matching
Paid Time-Off
Maternity Leave
Social Gatherings
Company Retreats

Drive groundbreaking AI research at Microsoft as a Principal Research Engineer in the AI Frontiers lab, focusing on reinforcement learning and next-gen AI models.

xAI Hybrid Palo Alto, California, United States
Posted 15 hours ago

Seek an AI Engineer & Researcher at xAI in Palo Alto to design and develop intuitive AI-human interaction models combining HCI expertise and AI engineering.

Photo of the Rise User

An opportunity as Scientist I at Eurofins Environment Testing in Pomona to conduct environmental sample analysis and laboratory procedures supporting safety and sustainability.

Photo of the Rise User

Support and lead critical medical affairs functions for Rheumatology at AbbVie, driving strategy execution and scientific engagement to impact patient care and market success.

xAI Hybrid Palo Alto, California, United States
Posted 16 hours ago

Contribute to cutting-edge reasoning efficiency AI models at xAI, developing scalable and cost-effective LLM solutions in a collaborative and high-impact environment.

xAI Hybrid Palo Alto, California, United States
Posted 16 hours ago

Innovative AI company xAI is seeking a skilled AI Engineer & Researcher to work on advanced multimodal large language model training in Palo Alto with a flexible hybrid work model.

Posted 7 hours ago

A research-driven software engineer role at UT Austin developing advanced applications in remote sensing, geospatial data analysis, and machine learning within a leading applied research laboratory.

Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied... a unique, hypothesis-driven innovation proces...

10 jobs
MATCH
Calculating your matching score...
FUNDING
SENIORITY LEVEL REQUIREMENT
TEAM SIZE
SALARY RANGE
$150,000/yr - $220,000/yr
EMPLOYMENT TYPE
Full-time, onsite
DATE POSTED
July 26, 2025
Risa star 🔮 Hi, I'm Risa! Your AI
Career Copilot
Want to see a list of jobs tailored to
you, just ask me below!