Post Doctoral Research Scholar - job 1 of 2

Thanks for your interest in Children's Mercy!

Do you envision finding a meaningful role with an inclusive and compassionate team? At Children’s Mercy, we believe in making a difference in the lives of all children and shining a light of hope to the patients and families we serve. Our employees make the difference, which is why we have been recognized by U.S. News & World Report as a top pediatric hospital, for eleven consecutive years.

Children’s Mercy is in the heart of Kansas City – a metro abounding in cultural experiences, vibrant communities and thriving businesses. This is where our patients and families live, work and play. This is a community that has embraced our hospital and we strive to say thanks by giving back. As a leader in children’s health, we engage in meaningful programs and partnerships throughout the region so that we can improve the lives of children beyond the walls of our hospital.

Overview

This is a two-year post-doctoral appointment (with possible renewal) to provide advance research training to individuals with a doctoral degree in the biological sciences and to further the basic and translational research goals in the Children's Research Institute. The postdoctoral research fellow will conduct high quality research in basic and translational science. Our laboratory has demonstrated that Crk and CrkL play essential roles in cell proliferation, morphology, motility, and transformation. Our laboratory will develop specific inhibitors of Crk and CrkL to further elucidate biological functions of Crk and CrkL and to test feasibility of Crk and CrkL as novel therapeutic targets for cancer treatment. The postdoctoral research fellow will make a leading role in developing and characterizing inhibitors of Crk and CrkL under close supervision of a junior faculty member. First, the postdoc will develop biochemical and cell-based screening systems for Crk/CrkL inhibitors. Second, the postdoc will collaborate with high throughput screening core facilities to identify specific inhibitors. Third, the postdoc will study inhibitors' structure-function relationship to improve affinity, specificity, and bioavailability. Then, the postdoc will use the inhibitors to characterize biological roles of Crk and CrkL in normal cells, tumor cell lines, and tumor specimen from patients using in vitro cell culture and transplantation/spontaneous mouse models.

At Children’s Mercy, we are committed to ensuring that everyone feels welcomed within our walls. A successful candidate for this position will join us as we strive to create a workplace that reflects the community we serve, as well as our core values of kindness, curiosity, inclusion, team and integrity.

Responsibilities

• Conducting original laboratory research in the general areas of biochemistry, cell biology, molecular biology, genomics, and neuroscience
• Analysis of research data

Qualifications

• Ph.D. or MD or related doctoral level degree in a relevant discipline and 1-2 years experience

Benefits at Children's Mercy

The benefits plans at Children’s Mercy are one of many reasons we are recognized as one of the best places to work in Kansas City. Our plans are designed to meet the changing needs of our employees and their families.

Starting Pay

Our pay ranges are market competitive. The pay range for this job begins at $28.39/hr, but your offer will be determined based on your education and experience.

Remote Work/Work from Home

This position is not eligible to work remotely, which means that the person hired will be required to work onsite at one of our Children’s Mercy locations and may not work from home.

EEO Employer/Disabled/Vet

Children’s Mercy hires individuals based on their job skills, expertise and ability to maintain professional relationships with fellow employees, patients, parents and visitors. A personal interview, formal education and training, previous work experience, references and a criminal background investigation all are factors used to select the best candidates. The hospital does not discriminate against prospective or current employees based on the race, color, religion, sex, national origin, age, disability, creed, genetic information, sexual orientation, gender identity or expression, ancestry or veteran status. A drug screen will be performed upon hire. Children’s Mercy is smoke and tobacco free.