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Software Engineer, Backend

Location: Flexible, should be able to travel to the SF bay area frequently.

Death is our only foe.

Blueprint was founded by Bryan Johnson, who has the world’s best comprehensive biomarkers. He is quantitatively the healthiest person on the planet.

Blueprint is methodically built on science. Bryan freely shares his protocol, learnings and data with everyone to use. Blueprint has also developed a family of nutritional products to make the benefits of the Blueprint protocol affordable and available to all.

We’re a small, tightknit team working to clean up the global food supply, provide healthy food to everyone, and build Don’t Die into the most influential ideology in the world. We move quickly, work efficiently, and enjoy an environment defined by competence

We’re looking for a Backend Software Engineer who loves to build things that matter. You’ll help architect and implement the foundation of Blueprint’s core systems, from data pipelines and APIs to AI integrations that make sense of complex biological data.

This is an opportunity to join Blueprint at the very beginning. You’ll work directly with product and design to build scalable services that will power intelligent, health-optimizing user experiences.

We’re building fast, experimenting constantly, and learning as we go. If you love working on challenging systems, writing clean code, and shaping the technical DNA of an early product, this is for you.

Position Responsibilities

  • Design, build, and maintain scalable backend systems and APIs from the ground up.
  • Write clean, maintainable, well-tested code that powers high-performance experiences.
  • Collaborate closely with product and design to integrate large language models (LLMs) and data-driven features.
  • Architect infrastructure that supports real-time data processing and intelligent insights.
  • Develop tools and services to diagnose, monitor, and optimize system performance.
  • Contribute to early architectural decisions, ensuring the system can scale gracefully.
  • Document designs, write thoughtful technical specs, and participate in peer reviews.

Basic Qualifications

  • 3+ years of experience building and shipping high-scale backend systems.
  • Fluent in at least one modern programming language such as Python, Go, Java, or Rust.
  • Strong computer science fundamentals including data structures, algorithms, distributed systems, and databases.
  • Hands-on experience building and consuming APIs and working with modern cloud infrastructure (AWS, GCP, or similar).
  • Excellent communication and collaboration skills, especially in cross-functional teams.
  • Curiosity and enthusiasm for applying AI and LLMs to real-world applications.

Preferred Skills

  • Experience designing systems that handle high data throughput or complex data processing.
  • Familiarity with AI/ML pipelines, model deployment, or LLM integration.
  • Knowledge of search systems, streaming data frameworks, or vector databases.
  • Background in health tech, analytics, or personalization systems.
  • Contributions to open-source projects or building products from 0 to 1.

Salary Range: $180,000 - $250,000 + equity + benefits

Average salary estimate

$215000 / YEARLY (est.)
min
max
$180000K
$250000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

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Full-time, remote
DATE POSTED
October 11, 2025
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